Non-uniform hydrogenation catalyst 's-PICA catalyst'
The ketone that had given up on the asymmetric reaction has become an optically active alcohol with high enantioselectivity!
This is a new asymmetric hydrogenation ruthenium catalyst developed in collaboration with Professor Okuma from Hokkaido University, featuring a unique substrate applicability range that has never been seen before. It efficiently converts ketones into optically active alcohols with high efficiency and high enantioselectivity. By selecting the reaction conditions, it is also possible to reduce keto esters to diols. The catalyst is suitable for bulk supply, making it useful for industrial processes. **Features** - Unique substrate applicability range: It hydrogenates bulky multi-substituted ketones, unprotected heteroaromatic ketones, and keto esters with high efficiency and high enantioselectivity, which conventional catalysts could not efficiently react with. - Proven performance at kg scale: There is a track record of asymmetric hydrogenation reactions at tens of kg scale. Reactions are also possible with a substrate/catalyst molar ratio (S/C) of over 10,000. For more details, please download the catalog or feel free to contact us.
- Company：関東化学株式会社 バイオケミカル部
- Price：Other
